Gene interactions and pathways from curated databases and text-mining

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CA2 — F10

Text-mined interactions from Literome

Ouellette et al., Blood Coagul Fibrinolysis 1992 : All of the antibodies bound both human factor X and factor Xa in a solid-phase ELISA and binding of the antibodies was not affected by removal of Ca2+ with EDTA
Lawson et al., J Biol Chem 1991 : The activation of human coagulation factor IX by human tissue factor.factor VIIa.PCPS.Ca2+ ( TF.VIIa.PCPS.Ca2+ ) and factor Xa.PCPS.Ca2+ enzyme complexes was investigated
van Dieijen et al., Thromb Haemost 1985 : The activation of blood coagulation factor X by factor IXa is strongly stimulated by the non-enzymatic cofactors phospholipid, Ca2+ and activated factor VIII
Nesheim et al., J Biol Chem 1981 : The Ca2+ dependent interactions of the inactivated factor Xa with its cofactors, phospholipid and activated factor V ( factor Va ), were studied through alterations of fluorescence polarization values of dansyl moiety of the modified enyme ... In the presence of phospholipid and Ca2+ , factor Va and factor Xa interacted with 1 : 1 stoichiometry, an interaction characterized by markedly enhanced polarization
Taneda et al., J Biochem 1994 : Prothrombin is a vitamin K-dependent plasma protein composed of several functional domains, which is proteolytically activated into thrombin by factor Xa in the presence of factor Va, Ca2+ , and phospholipids
Jesty et al., Biochemistry 1994 : Over a TFPI range of 0-1 nM, the rate of inhibition of factor Xa , in the presence of Ca2+ and anionic phospholipid vesicles at 37 degrees C, was proportional to TFPI concentration, giving an association rate, k1, of 0.96 x 10 ( 9 ) M-1 min-1