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ANGPT2 — NPPA

Text-mined interactions from Literome

Hannken et al., American journal of physiology. Renal physiology 2001 (Hypertrophy) : Although ANP and ANG II both stimulate generation of reactive oxygen species, ANP additionally induces expression of MKP-1, leading to interference with ANG II-mediated MAP kinase phosphorylation
Golos et al., Kidney Blood Press Res 2002 : In podocytes, Ang II induces rise in intracellular calcium concentration, whereas ANP stimulates generation of cGMP
Reis et al., Exp Physiol 2007 : In contrast SNAP blocked the AVP, OT and ANP release, as well as antidiuretic and natriuretic responses induced by ANG-II
Bie et al., Am J Physiol Regul Integr Comp Physiol 2009 : Metoprolol per se did not affect MAP, heart rate, or sodium excretion significantly, but reduced PRC and ANG II by 30-40 %, increased plasma atrial natriuretic peptide (ANP) , and tripled potassium excretion
Marsh et al., Amino Acids 2011 (Diabetes Mellitus, Type 2...) : ANG II and PE significantly increased levels of ANP and a-actin and phosphorylation of p38 and ERK in the non-diabetic but not in the diabetic group ; phosphorylation of Akt was unchanged irrespective of group or treatment
Oh et al., Peptides 2011 (Cardiomyopathy, Hypertrophic...) : However, the direct effect of Ang II on the secretion of atrial natriuretic peptide (ANP) is unclear
Parthasarathy et al., Mol Cell Biochem 2013 : Normal and NPR-A suppressed adult CF cells were treated with ANG II ( 10 ( -7 ) M ) in the presence and absence of ANP ( 10 ( -8 ) M ) for 24 h. Total collagen concentration, activity and expression of MMP-2 and MMP-9, and nuclear translocation of Nuclear factor-kappaB ( NF-?B-p50 ) were studied
Fujisaki et al., J Clin Invest 1995 : BNP was more potent than ANP to inhibit ANG II- and ET-1 stimulated DNA synthesis, whereas BNP and ANP were almost equipotent in stimulating cGMP generation in cardiac fibroblasts
Eiskjaer et al., Eur J Clin Invest 1996 : ANG II + ANP : during a background ANG II infusion, ANP still increased fractional excretion of sodium
Soualmia et al., J Cardiovasc Pharmacol 1997 : We concluded that Ang II induced IP production and ANP release through AT1 receptors