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NOS2 — ZGLP1
Text-mined interactions from Literome
Jimenez-Feltstrom et al., Cell Tissue Res 2005
:
The
GLP-1 induced suppression of glucose stimulated
iNOS activity and expression and its stimulation of insulin release is, at least in part, PKA dependent, since the PKA inhibitor H-89 reverses the effects of GLP-1
Salehi et al., PloS one 2008
(Diabetes Mellitus, Experimental...) :
The incretin hormone
GLP-1 , which is used in clinical practice
suppressed iNOS and ncNOS expression and activity with almost full restoration of insulin release and partial restoration of glucagon release
Chai et al., Diabetes 2012
:
After confirming that
GLP-1 potently
stimulates nitric oxide ( NO ) synthase ( NOS ) phosphorylation in endothelial cells, overnight fasted adult male rats received continuous GLP-1 infusion ( 30 pmol/kg/min ) for 2 h plus or minus NOS inhibition