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HDAC1 — WNT3

Text-mined interactions from Literome

Smith et al., J Biol Chem 2005 : These results suggest that inhibition of a PI3K/Akt/GSK3beta/beta-catenin/LEF axis and stimulation of HDAC1 cooperate to mediate the inhibitory effect of DEX on Wnt signaling and the osteoblast differentiation related cell cycle
Yamaguchi et al., Development 2005 : Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways
Sierra et al., Genes Dev 2006 : We conclude that, in addition to regulating the stability of beta-cat, APC facilitates CtBP mediated repression of Wnt target genes in normal, but not in colorectal cancer cells
Liu et al., Biochim Biophys Acta 2009 : Our data suggest that WNT signaling pathway plays important roles in the regulation of Hdac1 during the early stage of cardiomyocyte differentiation and that the downregulation of Hdac1 promotes cardiac differentiation
Debeb et al., Stem Cells 2012 (Breast Neoplasms...) : Moreover, while HDAC inhibitors upregulated ß-catenin expression and significantly increased WNT reporter activity, a TCF4 dominant negative construct abolished HDAC-inhibitor induced expansion of CSCs
Aldiri et al., Development 2013 (Wnt Signaling Pathway) : We also show that Wnt/ß-catenin signaling acting through the receptor Frizzled 5, but independent of Sox2, regulates expression of key PRC2 subunits in the developing retina