◀ Back to TNF

EPX — TNF

Text-mined interactions from Literome

Agnello et al., Brain Res 2002 (Arthritis, Experimental...) : EPO delayed the increase of TNF levels, without altering their peak levels, and markedly reduced those of IL-6 suggesting that the decreased inflammation and clinical score may be in part upon attenuation of IL-6
Jacobs-Helber et al., Blood 2003 (Leukemia, Erythroblastic, Acute) : EPO also could induce TNF-alpha expression in BAF3 and DA3 myeloid cells ectopically expressing EPOR
Lopez et al., J Interferon Cytokine Res 2003 : IFN-gamma ( 100 U/ml ) and TNF-alpha ( 1000 U/ml ) or IL-5 ( 200 pM ) caused a significant increase in the expression of the eosinophil peroxidase (EPO) and the major basic protein (MBP) genes
Chen et al., Exp Cell Res 2004 : BAF3 cells expressing a mutant EPOR with no cytoplasmic tyrosine residues were capable of triggering EPO dependent TNF-alpha synthesis and secretion, indicating that tyrosine docking sites in the EPOR were not required for EPO dependent TNF-alpha secretion
Kaiser et al., J Infect Dis 2006 (Disease Models, Animal...) : Tumor necrosis factor-alpha and interferon-gamma mRNA overexpression was inhibited by EPO , and treated mice had fewer brain hemorrhages
Wang et al., Zhonghua Xue Ye Xue Za Zhi 2007 (Anemia...) : TNF-alpha might inhibit EPO production and erythropoiesis, while IFN-gamma maybe directly inhibit erythropoiesis and be independent of EPO response inadequacy
Klemm et al., PloS one 2008 : EPO increased TNF-alpha levels and shifted the Bcl-x ( L ) to Bax ratio towards the pro-apoptotic Bax resulting in significantly increased hepatocellular apoptosis
Vachharajani et al., Pathophysiology : the official journal of the International Society for Pathophysiology / ISP 2010 : Results : EPO attenuated the LA, PA, BBB and behavioral dysfunctions and serum TNF levels 4h after CLP in both WT and ob/ob mice, and P-sel in ob/ob CLP mice
Spessotto et al., Eur J Immunol 1995 (Lymphoma, B-Cell) : Human eosinophil peroxidase enhances tumor necrosis factor and hydrogen peroxide release by human monocyte derived macrophages ... In this study, we report the effect of eosinophil peroxidase (EPO) , a basic protein contained in eosinophils that binds to several cell types including macrophages, on tumor necrosis factor (TNF) production and hydrogen peroxide release by human monocyte derived macrophages
Jelkmann et al., Ann N Y Acad Sci 1994 (Anemia...) : IL-1, TNF-alpha , and possibly other cytokines could contribute to defective EPO production in renal and nonrenal immune responses