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CXADR — PLD2
Text-mined interactions from Literome
Huang et al., Am J Physiol Cell Physiol 2004
:
To determine whether the receptor also couples to Galpha12/13, we investigated the signaling pathway by which the
CaR regulates
phospholipase D ( PLD ) , a known Galpha12/13 target
Kifor et al., J Bone Miner Res 1997
:
Moreover, high Ca2+ ( o ) -stimulated PLD activity was abolished following down-regulation of PKC by overnight phorbol myristate acetate ( PMA ) pretreatment, suggesting that
CaR mediated
activation of
PLD depends largely upon stimulation of PKC