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PCNA — PI3
Text-mined interactions from Literome
Medina et al., J Biol Chem 2000
:
Moreover, TSH through PKA pathway increases cyclin dependent kinase 2 levels, whereas
PI 3-kinase signaling
increases cyclin E levels
Uttamsingh et al., J Biol Chem 2003
:
In conclusion, we have adopted an experimental system enabling us to study the signaling pathways in cells grown under anchorage independent conditions and have identified matrix independent activation of PI 3-kinase and Stat3 signaling functions, as well as the
PI 3-kinase dependent increase of
cyclin A-associated Cdk2 kinase activity, to be critical for the Ros-PTK induced anchorage independent growth