◀ Back to PI3
HDAC1 — PI3
Text-mined interactions from Literome
Aoukaty et al., J Biol Chem 2002
(Lymphoproliferative Disorders) :
We report here a
role for
phosphoinositide 3-kinase (PI3K) in the recruitment and association of
SAP/SH2D1A to 2B4 in human NK cells
Shimizu-Hirota et al., Genes Dev 2012
:
In turn, MT1-MMP dependent
PI3Kd activation
regulates the immunoregulatory
Mi-2/NuRD nucleosome remodeling complex that is responsible for controlling macrophage immune response
Moskowitz et al., Curr Oncol Rep 2012
(Hodgkin Disease) :
Additional agents that have demonstrated activity in HL include
histone deacetylase inhibitors, such as panobinostat, entinostat, and mocetinostat,
PI3-kinase/Akt/Mtor pathway
inhibitors , such as everolimus, as well as lenalidomide and bendamustine