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EGR1 — PI3

Text-mined interactions from Literome

Shin et al., EMBO J 2006 : Our results demonstrate that phosphoinositide 3-kinase (PI3K) signaling is necessary for oncogenic H-Ras mediated reduction of Egr-1 gene expression
Lau et al., Oncogene 2011 (Ovarian Neoplasms) : In this study, we showed that loss of E-cadherin induced ovarian cancer cell growth and constitutive activation of phosphoinositide 3-kinase (PI3K)/Akt signaling by the inhibition of phosphatase and tensin homolog (PTEN) transcription through the downregulation of early growth response gene 1 (Egr1)
Brüning et al., Mol Cell Biol 1997 : Expression of IRS-1 in IRS-1-deficient cells by retroviral gene transduction restores IGF-1 stimulated mitogenesis, PI 3-kinase activation, and c-fos and egr-1 induction in proportion to the level of reconstitution