Gene interactions and pathways from curated databases and text-mining

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IL2 — OPRM1

Text-mined interactions from Literome

Kraus et al., Front Biosci (Schol Ed) 2009 : In this review, the up-regulation of human mu-opioid receptor gene expression in neuronal and immune effector cells by interleukin-1 , interleukin-4, interleukin-6 and tumor necrosis factor, as well as its down-regulation by interferon-gamma and granulocyte/macrophage colony stimulating factor will be summarized along with molecular mechanisms, such as transcription factor-promoter-interactions
Cox et al., Int J Immunopharmacol 1988 : At the suboptimal concentration of PHA, 8-MOP ( 140 microM ) caused a sustained inhibition of lymphocyte proliferation, IL-2 production/accumulation and IL-2 receptor expression