Gene interactions and pathways from curated databases and text-mining

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NOTCH1 — NRARP

Text-mined interactions from Literome

Krebs et al., Dev Biol 2001 : Thus, Nrarp transcript levels are regulated by the level of Notch1 signaling in both cultured cell lines and mouse embryos
Pirot et al., Biochem Biophys Res Commun 2004 : Interestingly, increased Nrarp transcription was observed following induction of Notch signaling, suggesting the existence of a negative feedback loop
Ishitani et al., Nat Cell Biol 2005 : These findings reveal that Nrarp independently regulates canonical Wnt and Notch signalling by modulating LEF1 and Notch protein turnover, respectively
Van de Walle et al., Blood 2009 : High Notch activity increases DTX1, NRARP , and RUNX3 expression, genes that are down-regulated during alphabeta-lineage differentiation
Sewell et al., Dev Biol 2009 : These include Uncx, a somite gene required for rib and vertebral patterning, and Nrarp , a regulator of Notch/Wnt signaling in zebrafish and a cycling gene in mouse