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GP5 — IL4
Text-mined interactions from Literome
Sundar et al., Proc Natl Acad Sci U S A 1991
:
Human immunodeficiency virus
glycoprotein ( gp120 ) infused into rat brain
induces interleukin 1 to elevate pituitary-adrenal activity and decrease peripheral cellular immune responses
Oh et al., Naunyn Schmiedebergs Arch Pharmacol 2009
:
Suppressive
effect of CTB
glycoprotein ( 75 kDa ) on
IL-4 expression in primary cultured lymphocytes treated with di ( 2-ethylhexyl ) phthalate ... The results from these experiments indicated that the CTB
glycoprotein inhibits
IL-4 expression, not IL-10 expression, on the stage of Th2 cell differentiation induced by DEHP in T lymphocytes
Oh et al., J Cell Biochem 2010
(Anaphylaxis...) :
Our results revealed that the CTB
glycoprotein in the presence of DEHP
inhibits the release of histamine and expression of
interleukin (IL)-4 , IL-6, and TNF-alpha in RBL-2H3 cells ... The results from these experiments indicated that the CTB
glycoprotein inhibits release of histamine and expressions of
IL-4 , IL-6, and TNF-alpha via down regulations of PKC/MAPK and NF-kappaB on the stage of mast cell degranulation induced by DEHP
Lee et al., Int Immunopharmacol 2010
(Calcium Signaling...) :
Our results obtained from this study showed that ZPDC
glycoprotein ( 10mg/kg )
inhibited interleukin-4 (IL-4) , immunoglobulin E ( IgE ), and histamine are released in mouse serum
Lim et al., Cell Immunol 2010
:
Our results showed that the OFI
glycoprotein ( 5 mg/kg )
inhibited histamine and beta-hexosaminidase release, lactate dehydrogenase ( LDH ), and
interleukin 4 (IL-4) in mice serum
Oh et al., Inflammation 2011
(Hypersensitivity...) :
Our results revealed that the CTB
glycoprotein inhibited the activity of ß-hexosaminidase and production of IgE and
IL-4 in serum from DEHP treated mice
Oh et al., Immunol Invest 2011
:
Our results showed that CTB
glycoprotein inhibited the production of IgE and
IL-4 in serum from ovalbumin ( OVA ) -treated BALB/c mice ... The results from these experiments indicate that the CTB
glycoprotein inhibits release of ß-hexosaminidase, and production of IgE and
IL-4 via down regulation of MAPK/ NF-?B on the stage of mast cell degranulation
Lee et al., Mol Cell Biochem 2013
(Carcinoma, Hepatocellular...) :
The results revealed that the SJSZ
glycoprotein ( 10 mg/kg, BW )
inhibits the phosphorylation of MAPKs and expression of NF-?B, pSTAT6, IL-10, and
IL-4 ; and normalizes production of ROS and NO, and expression of iNOS, IL-12, and IFN-?
Lee et al., Inflammation 2013
:
The SJSZ
glycoprotein normalized production of NO and ROS and expression of inducible nitric oxide synthase, IFN-?, and IL-12 but
suppressed expression of pSTAT6,
IL-4 , IL-10, and CD163 positive cells
Kojima et al., J Pharmacobiodyn 1986
(Neoplasms, Experimental) :
Furthermore, this serum
glycoprotein was found to
enhance glucose consumption and
interleukin-1 production and cytotoxic activities of mouse peritoneal macrophages
Geiger et al., J Biol Chem 1988
(Liver Neoplasms, Experimental) :
Induction of alpha 1-acid
glycoprotein by recombinant human
interleukin-1 in rat hepatoma cells
Weston et al., Transpl Immunol 1995
(Kidney Failure, Chronic) :
E-Selectin is a 115-kDa cell surface
glycoprotein transiently expressed on vascular endothelium in
response to
interleukin-1 and tumour necrosis factor-alpha with a peak in expression at four hours
Fournier et al., Hepatology 1994
:
These results show that ( a ) phenobarbital acts directly on hepatocytes by increasing alpha 1-acid glycoprotein gene expression and ( b ) this effect is mediated by a specific mechanism independent of pathways involved in alpha 1-acid
glycoprotein induction by
interleukin-1 , interleukin-6 and glucocorticoids
Herbert et al., FEBS Lett 1993
:
Endotoxin ( LPS ),
interleukin-1 beta (IL-1) and tumor necrosis factor-alpha (TNF)
increased the expression of tissue factor, a membrane anchored
glycoprotein that initiates blood coagulation on the surface of cultured bovine aortic endothelial cells ( ABAE ) and human monocytes
Andrejko et al., Crit Care Med 1996
(Sepsis) :
To test the hypothesis that after cecal ligation and puncture in the rat, there is increased expression of the tumor necrosis factor
(TNF)/interleukin-1 dependent , acute-phase reactant alpha 1-acid
glycoprotein in the liver, and that this change correlates temporally with increased abundance of TNF-alpha in the hepatic parenchyma but not with circulating concentrations of TNF-alpha
Temann et al., Am J Respir Cell Mol Biol 1997
:
Thus, transgenic mice that overexpress murine IL-4 selectively within the lung were used to study the
effect of
IL-4 on mucus
glycoprotein gene expression and mucin release ... Thus, the overexpression of
IL-4 locally within the lung enhances mucus glycoprotein synthesis by altering gene expression,
results in the accumulation of mucus
glycoprotein in nonciliated epithelial cells, and induces the release of mucus into the airway lumen
Tambur et al., Hum Immunol 1998
(Leukemia) :
IL-4 inhibits
P-glycoprotein in normal and malignant NK cells