Gene interactions and pathways from curated databases and text-mining

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IL10 — S100A8

Text-mined interactions from Literome

Endoh et al., J Immunol 2009 (RNA Virus Infections) : IL-10 dependent S100A8 gene induction in monocytes/macrophages by double stranded RNA
Goyette et al., Amino Acids 2011 (Inflammation) : The S100A8 gene induction in macrophages is dependent on IL-10 and potentiated by immunosuppressive agents
Abbas et al., Stroke 2012 (Carotid Artery Diseases...) : Our main findings were : ( 1 ) plasma levels of S100A12 were significantly higher in patients with carotid atherosclerosis compared with healthy control subjects with the highest levels in patients with the most recent symptoms ( ie, within 2 months ) ; ( 2 ) plasma levels of S100A8/S100A9 showed a modest increase in patients with symptoms in the previous 2 to 6 months but not in the other patients ; ( 3 ) mRNA levels of S100A8, S100A9, and S100A12 showed increased expression in atherosclerotic carotid plaques from patients with the most recent symptoms compared with the remaining patients ; ( 4 ) in THP-1 monocytes, activation of Toll-like receptors 2 and 4 increased mRNA levels of S100A8 , S100A9, and S10012 and interleukin-1ß , interferon ?, and releasate from thrombin activated platelets significantly enhanced the expression of S100A12