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FUT1 — IL10

Text-mined interactions from Literome

Sugita et al., Res Commun Mol Pathol Pharmacol 1999 : We investigated the effect of FUT-175 , a serine protease inhibitor, on the production of pro-inflammatory cytokines, interleukin-6 (IL-6) and interleukin-8 (IL-8), by monocytes stimulated with lipopolysaccharide (LPS)
Weng et al., Zhonghua Yi Xue Za Zhi 2002 : To investigate the effect of interleukin-10 (IL-10) on the activation of cultured rat hepatic stellate cells (HSC) induced by Kupffer cells ( KC ) and relevant mechanisms ... Through reducing cytokine production by KC, IL-10 inhibits the activation of cultured rat HSC induced by KC, which may play a protective role against liver fibrosis
Mattos et al., J Control Release 2012 (Liver Cirrhosis) : Immunohistochemical analysis of fibrotic livers of mice receiving treatment with IL-10 or its PEGylated forms, revealed a decrease in markers reflecting HSC and KC activation induced by 5PEG-IL10
Wang et al., J Biol Chem 1998 : Culture activation of HSC caused a distinct increase in IL-10 mRNA level compared with freshly isolated quiescent HSC ... These results demonstrate that activation of HSC causes enhanced autocrine expression of IL-10 which possesses a negative autoregulatory effect on HSC collagen production mediated at least in part by alpha1 ( I ) collagen transcriptional inhibition and stimulation of collagenase expression