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CRH — IL10
Text-mined interactions from Literome
Smith et al., J Neuroimmunol 1999
:
IL-10 enhances
corticotropin releasing factor (CRF) and corticotropin ( ACTH ) production in hypothalamic and pituitary tissues, respectively
Cambronero et al., Regul Pept 1992
:
Adrenalectomy does not change
CRF secretion
induced by
interleukin-1 from rat perifused hypothalami
Maes et al., Neuro Endocrinol Lett 2003
:
The aims of the present study were to examine i ) the
effects of
CRH , 10-9 M, 10 ( -8 ) M and 10 ( -7 ) M, on the stimulated production of IFNgamma,
IL-10 and tumor necrosis factor-alpha (TNFalpha) by human whole blood ; and ii ) whether CRH, 10 ( -9 ) M, 10 ( -8 ) M and 10 ( -7 ) M, may antagonize some of the negative immunoregulatory effects of 5-HT, 1.5 microg/mL or 15 microg/mL
Krause et al., Horm Metab Res 2007
:
alpha-Helical-CRF, a CRH antagonistic peptide, annulled the
CRH effect on SZ95 sebocyte proliferation and
interleukin secretion, while the non-peptidic CRH-R1 selective antagonist antalarmin inhibited the increased production of neutral lipids caused by CRH
Kageyama et al., J Endocrinol 2009
:
Among them,
interleukin (IL)-6 plays a role in the regulation of
CRF
Oh et al., J Allergy Clin Immunol 2012
(Dermatitis, Atopic) :
CRH mediated suppression of
IL-10 secretion from Treg cells might explain stress related exacerbations in patients with AD
Theoharides et al., Ann Allergy Asthma Immunol 2012
(Asthma...) :
CRH also
reduces T-regulatory cell production of
interleukin 10 , which in known to inhibit allergic mast cell activation
Sandi et al., Eur J Pharmacol 1995
:
This study investigated the possibility that nitric oxide ( NO ) acts as a mediator of
interleukin-1 induced
CRF release ... The concurrent treatment with NG-nitro-L-arginine and indomethacin ( 14 microM ) -- an inhibitor of prostaglandin production -- reduced
interleukin-1 induced
CRF release to the same level as NG-nitro-L-arginine alone, suggesting that prostaglandins might interact with NO on this interleukin-1 effect
Kakucska et al., Endocrinology 1993
:
Endotoxin induced
corticotropin releasing hormone gene expression in the hypothalamic paraventricular nucleus is
mediated centrally by
interleukin-1
Dudley et al., Am J Obstet Gynecol 1999
(Obstetric Labor, Premature...) :
The cytokine
interleukin 1
stimulates production of
corticotropin releasing hormone , and corticotropin releasing hormone in turn regulates cytokine production by immune effector cells