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ICAM1 — PIK3R1
Text-mined interactions from Literome
Arnold et al., J Immunol 2005
:
The virus induced
ICAM-1 up-regulation was
dependent on protein kinase C and A,
PI3K , and p38 MAPK activity
Amin et al., Blood 2006
:
Antisense oligodeoxynucleotides ( ODNs ) and inhibitors of Src,
PI3K , p38, and NFkappaB significantly
reduced rhMIF induced MN VCAM-1 and
ICAM-1 expression ( P < .05 )
Lin et al., J Cell Physiol 2007
(Lung Neoplasms) :
We initially observed that IL-1beta induced
ICAM-1 promoter activity was
attenuated by the inhibitors of Src ( PP1 ), PDGFR ( AG1296 ),
PI3-K ( LY294002 and wortmannin ), and Akt ( SH-5 ), revealed by reporter gene assay, Western blotting, and RT-PCR analyses ... The
involvement of Src and
PI3-K/Akt in IL-1beta induced
ICAM-1 expression was significantly attenuated by transfection of A549 cells with dominant negative plasmids of Src, p85 and Akt, respectively
Zhang et al., Wei Sheng Yan Jiu 2008
:
[
Involvement of EGF receptor and
PI3K in
ICAM-1 expression in human airway epithelial cells exposed to zinc sulfate ] ... The expression of
ICAM-1 mRNA and protein and
activation of epithelial growth factor receptor (EGFR) and
PI3K was determined using PCR and immunoblotting
Park et al., Br J Pharmacol 2013
:
A
PI3K specific inhibitor ( LY294002 ), Akt inhibitor VIII ( Akti ) and NF-?B inhibitors ( Bay-11-7082 and MG-132 )
attenuated the induction of
ICAM-1 by PGE2