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CTNNB1 — PCNA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Shtutman et al., Proc Natl Acad Sci U S A 1999
(Colonic Neoplasms) :
Cyclin D1 protein levels were
induced by
beta-catenin overexpression and reduced in cells overexpressing the cadherin cytoplasmic domain
Behari et al., J Hepatol 2007
(Carcinoma, Hepatocellular...) :
An associated inhibition of
beta-catenin dependent Tcf reporter activity, decreased levels of downstream target gene products glutamine synthetase and
cyclin-D1 , and decreased proliferation and survival of hepatoma cells was evident
Zhao et al., Cancer Biol Ther 2010
(Neoplasm Invasiveness...) :
Moreover, suppression of PDGF-D expression resulted in less
activation of
beta-catenin and its downstream effector genes,
cyclin D1 and matrix metalloproteinases, which are known to be involved in cell proliferation and invasion, respectively