Yalcin et al., Oncogene 2010
(Neoplasms, Experimental) :
Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling
Chua et al., Molecular cancer 2009
(Breast Neoplasms) :
Regulation of Akt ( ser473 ) phosphorylation by choline kinase in breast carcinoma cells
Ali et al., Invest New Drugs 2013
(Carcinoma...) :
Results show that ChK inhibited both Akt and JNK phosphorylation at key activation sites in ras transformed cells as well as human lung carcinoma cells ... This report establishes the dual inhibitory effect of ChK on both the Akt and JNK signaling pathways in ras transformed epithelial and human carcinoma cells