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AKT2 — CBFA2T2

Text-mined interactions from Literome

Komori et al., Clinical calcium 2006 : Phosphoinositide 3-kinase (PI3K)-Akt signaling enhances DNA binding of Runx2 and Runx2 dependent transcription, and Runx2 upregulates PI3K subunits ( p85 and p110 beta ) and Akt
Adochio et al., Endocrinology 2009 (Insulin Resistance) : Reduction in expression of either p85alpha or S6K1 achieved with small interfering RNA in the presence of myristoylated Akt rescued 3T3-L1 adipocytes from the insulin resistance induced by serine phosphorylation of IRS-1 and completely restored insulin stimulated activation of PI 3-kinase and glucose uptake
Yan et al., Cancer Res 2010 (Carcinoma, Hepatocellular...) : The interaction between RARgamma and p85alpha resulted in activation of Akt and NF-kappaB, critical regulators of the growth and survival of cancer cells
Cooper et al., PloS one 2011 : Similarly, depletion of the PI3K regulatory subunits p85a and p85ß by RNAi had no inhibitory effect on SopB dependent Akt phosphorylation
Bang et al., Neurosci Lett 2012 : The interaction between p85 and the C-terminal region of Rhes is enhanced upon growth factor treatment in vitro, while AKT translocation to the membrane is facilitated in the presence of Rhes or the Rhes-p85 complex