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AKT2 — CAMKK1

Text-mined interactions from Literome

Chen et al., J Biol Chem 2002 : We have also identified a novel interaction between CaMKK stimulated Akt and interleukin-1 receptor associated kinase 1 ( IRAK1 ), which plays a key role in IL-1beta induced NF-kappaB activation ... Taken together, these results indicate a novel regulatory mechanism for IL-1beta signaling and suggest that CaMKK dependent Akt activation inhibits IL-1beta induced NF-kappaB activation through interference with the coupling of IRAK1 to MyD88
Witczak et al., Diabetes 2007 : The objective of this study was to determine whether CaMKKalpha regulates skeletal muscle glucose uptake, and whether it is dependent on AMPK and/or Akt activation ... Akt ( Thr ( 308 ) ) phosphorylation was not altered by CaMKKalpha , and caCaMKKalpha plus insulin stimulation did not increase the insulin induced phosphorylation of Akt ( Thr ( 308 ) )
Fortin et al., J Neurosci 2012 : Specifically, BDNF mediated phosphorylation of threonine 308 ( T308 ) in AKT , a known substrate of CaMKK and an upstream activator of mTOR dependent translation, was prevented by ( 1 ) pharmacological inhibition of CaMKK with STO-609, ( 2 ) overexpression of a dominant negative CaMKK, or ( 3 ) short hairpin mediated knockdown of CaMKK