◀ Back to ABL1
ABL1 — CEBPA
Text-mined interactions from Literome
Perrotti et al., Nat Genet 2002
(Blast Crisis...) :
BCR-ABL suppresses
C/EBPalpha expression through inhibitory action of hnRNP E2 ... Our results indicate that
BCR-ABL regulates the expression of
C/EBPalpha by inducing hnRNP E2-which inhibits the translation of CEBPA mRNA
Schuster et al., Blood 2003
:
The
effects of
Bcr-Abl on
C/EBP transcription-factor regulation and neutrophilic differentiation are reversed by the Abl kinase inhibitor imatinib mesylate ... Importantly, incubation of 32D ( Bcr-Ablwt ) cells with the kinase inhibitor imatinib mesylate prior to G-CSF stimulation completely neutralized the
effects of
Bcr-Abl on granulocytic differentiation and on
C/EBPalpha and C/EBPepsilon expression