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CTSS — TNF

Text-mined interactions from Literome

Watari et al., Am J Pathol 1999 : TNF-alpha induced cathepsin S , MMP-1, -3, and -9 mRNA expression in a dose dependent manner : the maximal effect was observed at a concentration of 10 ng/ml, with appreciable increases observed at concentrations of 0.1 to 1.0 ng/ml
Liu et al., EMBO J 2003 : In addition to activating caspases, TNF-R1 stimulation causes the release of cathepsins , most notably cathepsin B, from the lysosome into the cytoplasm where they induce apoptosis
Klarić et al., Biochim Biophys Acta 2009 : Based on the use of pharmacological caspase inhibitors, the TNF-alpha induced caspase dependent apoptotic cell death in both cell lines, which was accompanied by lysosomal destabilization and the release of cathepsins in the cytosol
Caglič et al., Biol Chem 2013 : Stimulation of the cultivated chondrocytes with interleukin-1a and/or tumor necrosis factor a resulted in a time dependent increase in cathepsin S expression and induced its secretion into the conditioned media