Gene interactions and pathways from curated databases and text-mining

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APCS — TNF

Text-mined interactions from Literome

Chou et al., J Immunol 2005 (Berylliosis...) : Our results demonstrate that in the presence of APCs , beryllium induced strong proliferation responses of BAL CD4 ( + ) T cells, production of superoptimal concentrations of secreted proinflammatory cytokines, IFN-gamma, TNF-alpha , and IL-2, and up-regulation of numerous T cell surface markers that would promote T-T Ag presentation
Masli et al., Immunology 2009 : In response to TGF-beta, APCs increase their expression of tumour necrosis factor (TNF)-alpha and TNF receptor 2 (TNF-R2)
Rudnick et al., J Biol Chem 1993 (Inflammation) : In addition the cytokines interleukin-1, -6, and tumor necrosis factor mediate a decrease in hepatic SAP ( FP ) transcript levels in female hamsters but did not cause a significant elevation of SAP ( FP ) mRNA in livers of male hamsters
Sad et al., J Immunol 1997 : IL-2 synthesis was the most sensitive, as stimulation of IL-4 treated Tc1 cells with higher numbers of APCs partially restored IFN-gamma, TNF , and IL-10, but not IL-2, synthesis