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SETD2 — TGFB3
Text-mined interactions from Literome
Schäffer et al., Placenta 2003
:
To analyze how
HIF-1 regulates
TGF-beta 3 gene transcription, we cloned and sequenced the mouse TGF-beta 3 promoter region ... These results suggest that
TGF-beta 3 gene expression is directly
regulated by
HIF-1
Sánchez-Elsner et al., J Mol Biol 2004
(Anoxia) :
In the present work, a cooperative interaction between hypoxia,
mediated by the
HIF-1 complex, and
transforming growth factor-beta ( TGF-beta ), mediated by Smad3/4, was revealed in the Epo gene
Nishi et al., Endocrinology 2004
(Anoxia...) :
Our results provide evidence that
regulation of
TGF-beta3 promoter activity by
HIF-1 represents a mechanism for trophoblast differentiation during hypoxia
McMahon et al., J Biol Chem 2006
(Inflammation) :
Among others, recent studies indicated that
transforming growth factor ( TGF ) beta increases the expression of the regulatory HIF-1alpha subunit, and
induces HIF-1 DNA binding activity