Gene interactions and pathways from curated databases and text-mining

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PRL — RAB8A

Text-mined interactions from Literome

Johnston et al., J Exp Zool 1999 : MEL reduced PRL levels to basal levels and induced winter anagen 7 weeks earlier than controls
Di et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1997 : This work was to investigate whether melatonin (MEL) plays a role in the gene expression of prolactin (PRL) , by the Method of in situ hybridyzation ... Our results indicated that, at a higher concentration, MEL not only inhibits TRH ( thyrotropin releasing hormone ) stimulating PRL gene expression of anterior pituitary cell in newborn rat, but also exerts a direct inhibitory effect on PRL gene expression in vitro
Lee et al., Mol Cells 1999 : These data suggest that D2 and Mel1a may control the expression of PRL-GH genes in the rat placenta and its response to the extracellular changes of DA and melatonin secreted from the maternal organ ... However, Pit-1 may not be involved in the Mel1a induced inhibition of PRL-GH gene expressions in the rat placenta
Hauser et al., J Pineal Res 1989 : Serum PRL levels were similarly suppressed by MEL or SP exposure in E2-treated hamsters
Lincoln et al., Neuroendocrinology 1995 : There were changes in growth and moulting of the pelage correlated with the marked changes in the secretion of prolactin induced by MEL , but not related to the lesser effects of BROM and SULP
Juszczak et al., J Physiol Pharmacol 1996 : However, Mel facilitated the release of OT, but prevented the release of PRL after hypertonic saline administration
Juszczak et al., Brain Res Bull 1997 : In the present study we investigated the effect of exogenous MEL , administered intracerebroventricularly ( ICV ), on suckling induced OT and prolactin (PRL) release in the urethane anesthetized rat
Rose et al., Comp Biochem Physiol A Mol Integr Physiol 1998 : In the spring, haloperidol (HAL) increased PRL concentrations and induced summer anagen earlier than controls, whereas melatonin (MEL) inhibited PRL secretion and completely blocked summer anagen