O'Connor et al., Exp Cell Res 2005
(Lymphoma, B-Cell) :
Additionally, we found evidence that PIR IkappaBalpha degradation controls constitutive NF-kappaB activation in certain multiple myeloma cells
Markovina et al., Mol Cancer Res 2008
(Multiple Myeloma) :
Further elucidation of the mechanism of PIR NF-kappaB regulation could lead to the identification of novel diagnostic biomarkers and/or therapeutic targets for MM treatment