Gene interactions and pathways from curated databases and text-mining

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KDR — MMP9

Text-mined interactions from Literome

Yao et al., J Cereb Blood Flow Metab 2007 (Arteriovenous Malformations) : Inhibiting IL-6 induced KDR could reduce MMP-9 activity at least 50 % compared with the control group ( P < 0.05 )
Adya et al., Cardiovasc Res 2008 : Inhibition of VEGFR2 and VEGF [ by soluble FMS-like tyrosine kinase-1 ( sFlt1 ) ] down-regulated visfatin induced MMP induction
Abdul Muneer et al., Arterioscler Thromb Vasc Biol 2012 (Disease Models, Animal...) : The mechanisms of cerebral vascular dysfunction and neuroinflammation by MMP mediated degradation of VEGFR-2 in alcohol ingestion
dela Paz et al., Biochem Biophys Res Commun 2013 : Early VEGFR2 activation in response to flow is VEGF dependent and mediated by MMP activity ... Finally, we show that flow induced VEGFR2 activation is attenuated in the presence of the broad spectrum matrix metalloproteinase ( MMP ) inhibitor, GM6001
Chen et al., Nan Fang Yi Ke Da Xue Xue Bao 2013 : MMP-2/MMP-9 inhibitor III did not obviously affected the expression of PTEN, VEGF or Flk-1 as compared with the non transfected or empty vector transfected cells