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IL13 — IL3
Text-mined interactions from Literome
Yoshimoto et al., Proc Natl Acad Sci U S A 1999
(Hypersensitivity...) :
Here we show that basophils and mast cells derived by culture of bone marrow cells with IL-3 for 10 days express IL-18Ralpha chain and that basophils produce large amounts of IL-4 and
IL-13 in
response to stimulation with
IL-3 and IL-18 ... Injection of IL-12 and IL-18 inhibits IgE production in helminth infected wild-type mice and abolishes the capacity of their basophils to produce IL-4 and
IL-13 in
response to stimulation either with
IL-3 and IL-18 or with FcepsilonR cross-linkage
Sin et al., J Allergy Clin Immunol 2001
(Hypersensitivity) :
Nerve growth factor or
IL-3 induces more
IL-13 production from basophils of allergic subjects than from basophils of nonallergic subjects
Schroeder et al., Clin Exp Allergy 2001
:
Desloratadine had a lesser effect regarding inhibition of the
IL-13 secreted in
response to
IL-3 and PMA
Zirngibl et al., Mol Cell Biol 2002
:
Bone marrow derived Fps/Fes-null macrophages showed no defects in granulocyte-macrophage colony stimulating factor-,
interleukin 6 (IL-6)-, or
IL-3 induced
activation of signal transducer and activator of transcription 3 ( Stat3 ) and Stat5A or LPS induced degradation of I kappa B or activation of p38, Jnk, Erk, or Akt
Chen et al., J Allergy Clin Immunol 2003
:
Effects of IFN-alpha on
IL-3 mediated
IL-13 secretion and basophil survival were also tested ... Furthermore, IFN-alpha blocked
IL-13 secretion directly
induced by
IL-3
Eskandari et al., Br J Pharmacol 2004
:
The
IL-3 induced generation of IL-4,
IL-13 and histamine was inhibited to a statistically significant ( P < 0.05 ) extent, only by compounds that act as inhibitors of PDE4
Melk et al., Transplantation 2004
(Growth Disorders...) :
During rhGH therapy in children with transplants,
interleukin (IL)-2 production increased threefold at 4 weeks, and IL-4 and
IL-13 increased by 70 % at 12 weeks
Gibbs et al., Int Immunopharmacol 2005
:
Here, we compared the abilities of
IL-3 and NGF to
stimulate basophil histamine, IL-4 or
IL-13 release, either directly or in conjunction with IgE dependent stimulation and assessed the intracellular signals responsible
Matsuzaki et al., Cancer Sci 2006
:
We have demonstrated previously that the Th1-cytokine conditioned bone marrow derived dendritic cell ( BMDC ) subset BMDC1 ( generated in the presence of granulocyte-macrophage colony stimulating factor [GM-CSF ]
+ interleukin [ IL]-3 + interferon [ IFN]-gamma+ IL-12 )
induces a much stronger type 1 immune response than BMDC0 ( GM-CSF +
IL-3 )
Kondo et al., Int Immunol 2008
(Hyperplasia...) :
Basophils, comprising IL-18Ralpha ( + ) cells ( 14.2 % ) and IL-33Ralpha ( + ) cells ( 34.6 % ), and mast cells, comprising IL-18Ralpha ( + ) cells ( 2.0 % ) and IL-33Ralpha ( + ) cells ( 95.6 % ), produce IL-4, IL-6,
IL-13 , granulocyte macrophage colony stimulating factor ( GM-CSF ) and chemokines ( RANTES, MIP-1alpha, MIP-1beta and MCP-1 ), upon stimulation with IL-18 and/or IL-33 in the
presence of
IL-3
Cohen et al., Immunol Lett 1991
:
We have studied the production of interleukin-1 (IL-1),
interleukin-6 (IL-6) and tumor necrosis factor (TNF) by mouse peritoneal macrophages triggered by lipopolysaccharide (LPS) in the
presence or absence of
IL-3
Haber et al., Exp Parasitol 2009
(Hyperalgesia...) :
Leishmania major :
interleukin-13 increases the infection induced hyperalgesia and the levels of interleukin-1beta and
interleukin-12 in rats
Cavaillon et al., Cell Immunol 1990
:
Induction of
interleukin-3 by
interleukin-1 in the absence of other exogenous stimuli
Junttila et al., J Allergy Clin Immunol 2013
:
Efficient cytokine induced
IL-13 production by mast cells
requires both IL-33 and
IL-3 ... Basophils follow the same rule ; splenic basophils produce
IL-13 in
response to IL-18 or IL-33 plus
IL-3
Ochensberger et al., Blood 1996
:
Here we show that human basophils produce
IL-13 in
response to IgE-receptor (IgER) crosslinking,
IL-3 , IL-3 plus C5a, but not C5a alone
Redrup et al., J Immunol 1998
:
The induction of
IL-13 secretion also occurred in
response to
IL-3 alone, without concomitant secretion of either IL-4 or histamine