◀ Back to IL13

IL13 — SOCS1

Text-mined interactions from Literome

Hebenstreit et al., J Immunol 2003 : IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6 binding motifs located upstream of the transcription initiation site ... We show here that SOCS-1 expression can be induced in the human epithelial lung cell line A549 by IL-4 and IL-13 ... STAT6 is therefore required for IL-4-IL-13 dependent SOCS-1 expression in A549 cells, and the three identified binding motifs cooperate to induce maximal transcription
Hebenstreit et al., Mol Immunol 2005 : SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells
Zhao et al., J Biol Chem 2007 (Asthma) : Furthermore, pretreatment with LPA ( 1 microM, 6 h ) attenuated IL-13 induced eotaxin-1 and SOCS-1 gene expression
Albanesi et al., J Immunol 2007 : We further demonstrate that IL-4 and IL-13 activate STAT-6 and induce the suppressors of cytokine signaling (SOCS)-1 and -3
Martinez-Nunez et al., J Biol Chem 2011 (Asthma) : Finally we also demonstrate that miR-155 affects the IL-13 dependent regulation of several genes ( SOCS1 , DC-SIGN, CCL18, CD23, and SERPINE ) involved in the establishment of an M2/pro-Th ( 2 ) phenotype in macrophages
Park et al., J Allergy Clin Immunol 2013 (Nasal Polyps...) : Nasal epithelial cell culture was used to elucidate the effect of IL-4, IL-5, IL-6, IL-10, IL-13 , IFN-?, TNF-a, and TGF-ß1 on SOCS1 and SOCS3 expression in sinus mucosa ... SOCS1 was induced by IL-4, IL-13 , IFN-?, and TNF-a, while SOCS3 expression was upregulated by IL-6, IL-13, IFN-?, and TNF-a