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FLT3 — HNRNPH1

Text-mined interactions from Literome

Vollstedt et al., J Exp Med 2003 (Herpes Simplex...) : Flt-3 ligand (FL) , a hematopoetic growth factor, increases the number of dendritic cells (DCs) , B cells, and natural killer cells in adult mice but the effect in neonates was unknown
Walzer et al., J Allergy Clin Immunol 2005 (Disease Models, Animal...) : By using various experimental models, the role of FLT3L dependent DCs in the priming of naive T cells, the presentation of inhaled antigen to previously primed T H 2 cells, and intranasal tolerance induction was addressed ... FLT3L dependent DCs were not required for the presentation of inhaled antigen to previously primed T H 2 cells, and normal induction of T-cell tolerance in response to inhaled antigen was observed in FLT3L knockout mice ... FLT3L dependent DCs are not required for the development and maintenance of airway inflammation or for the induction of intranasal tolerance
Darrasse-Jèze et al., J Exp Med 2009 (Diabetes Mellitus, Type 1...) : In addition to their effects on T cells, T reg cells are essential for maintaining normal numbers of dendritic cells (DCs) : when T reg cells are depleted, there is a compensatory Flt3 dependent increase in DCs
Hennies et al., Clin Exp Immunol 2011 (Neoplasms) : FLT3L treatment augmented the absolute numbers of these DCs , but did not change their activation status nor their capacity to prime antigen-specific T cells
Fujita et al., Immunol Lett 2011 (Multiple Myeloma) : FLT3-ITD , CA-N-Ras, and TEL/PDGFRß aberrantly induced programmed death ligand-1 (PD-L1) expressing DCs
Zhu et al., PloS one 2012 : FLT3L increased both monocyte derived DCs and lymphoid derived DCs from mouse bone marrow cultured in vitro ... We used shRNA gene knockdown and chromatin immunoprecipitation to demonstrate that PU.1 is required for the effects of GM-CSF or FLT3L on monocyte derived DCs
Siena et al., Exp Hematol 1995 (Neoplasms) : We show that the GM-CSF-plus-TNF-alpha dependent ex vivo generation of DCs from mobilized CD34+ cells is 2.5-fold enhanced by flk-2/flt-3 ligand or c-kit ligand ( stem cell factor ) and five-fold enhanced by a combination of these growth factors