Gene interactions and pathways from curated databases and text-mining

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DBT — EPO

Text-mined interactions from Literome

Gao et al., Planta Med 2008 : In addition, the DBT induced EPO expression could be abolished by pre-treatment with U0126, a mitogen activated kinase inhibitor
Zheng et al., J Ethnopharmacol 2010 : Pharmacological results indicate that DBT can stimulate the production of erythropoietin (EPO) , a specific hematopoietic growth factor, in cultured cells ... In order to reveal the mechanism of DBT 's hematopoietic function, this study investigated the activity of the DBT induced EPO expression and the upstream regulatory cascade of EPO via hypoxia induced signaling in cultured kidney fibroblasts ( HEK293T ) ... Our study indicates that HIF pathway plays an essential role in directing DBT induced EPO expression in kidney