Gene interactions and pathways from curated databases and text-mining

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CD4 — CD83

Text-mined interactions from Literome

Munster et al., Int Immunol 2004 : CD83 is a marker of dendritic cell ( DC ) differentiation/activation and its expression in the mouse thymus contributes to CD4 ( + ) T lymphocyte development
Kuwano et al., Int Immunol 2007 : In mice, CD83 expression by thymic stromal cells regulates CD4 ( + ) T cell development, with CD83 ( -/- ) mice demonstrating dramatic reductions in both thymus and peripheral CD4 ( + ) T cells
Kretschmer et al., Immunol Lett 2008 : CD83 expression levels did not significantly affect CD4 ( + ) T cell activation in vivo, but a weak positive correlation of CD83 expression with CD4 ( + ) T cell activation was observed in vitro under suboptimal stimulation conditions
Su et al., J Immunol 2009 : This study supports the novel mechanism of ubiquitination by GRAIL, identifies CD83 as a substrate of GRAIL, and ascribes a role for CD83 in CD4 T cell activation
Chen et al., Hybridoma (Larchmt) 2011 : CD83 , a maturation marker for human and mouse dendritic cells (DCs), plays a critical role in CD4 ( + ) T cell development as well as peripheral immune regulation