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BMP7 — SLC22A3

Text-mined interactions from Literome

Tan et al., Zhonghua Yi Xue Za Zhi 2005 : To examine the effect of Bone Morphogenetic protein-7 (BMP-7) on Monocyte chemoattractant protein-1 ( MCP-1 ) induced epithelial-myofibroblast transition ( EMT ) in cultured renal proximal tubular cells ( HK-2 ) and the relationship between TGF-beta1-smad 3 expressions and MCP-1 induced EMT ... BMP-7 may partially inhibit MCP-1 induced EMT and this effect is related to the downregulated expression of TGF-beta1 and Smad 3 of the cells
Okagawa et al., Dev Biol 2007 : These results provide evidence that BMP signaling through the AV endocardium is required for the EMT and the activation of the BMP receptor in the endocardium can promote AV EMT in the chick
Ohta et al., Development 2007 : These indicate that the inhibition of Bmp signaling by temporal and/or spatial Nog expression suppresses EMT and leads to the cessation of the ingressive cell movement from the VER at the end of gastrulation
Lee et al., J Korean Med Sci 2007 (Fibrosis) : We and others also observed that bone morphogenetic protein-7 (BMP-7) prevented EMT in HPMC
Dudas et al., Nephrol Dial Transplant 2009 : In the present study, despite confirming BMP-7 regulation of receptor expression and induction of downstream signalling events, we were unable to demonstrate BMP-7 inhibition of EMT in either primary or immortalized human proximal tubule cells
Murray et al., PloS one 2008 (Disease Models, Animal...) : BMP-7 has been reported to inhibit renal fibrosis and TGFbeta1 induced epithelial-mesenchymal transition (EMT) , in part through negative interactions with TGFbeta1 induced Smad 2/3 activation ... We then determined the effect of BMP-7 on TGFbeta1 induced EMT in lung epithelial cells and collagen production by human lung fibroblasts
Xu et al., Nephron. Experimental nephrology 2010 : We therefore designed a method to investigate the mechanism by which BMP-7 inhibits CSA induced EMT in cultured human renal proximal tubular epithelial ( HK-2 ) cells and whether BMP-7 can antagonize CsA induced profibrogenic effects ... These data suggest that BMP-7 can block CsA induced EMT by downregulating the expression of CTGF, a downstream mediator of EMT
Loureiro et al., Nephrol Dial Transplant 2010 (Fibrosis) : Herein, we analysed the modulating role of BMP-7 on EMT of MC in vitro and its protective effects in a rat PD model
Yan et al., Am J Pathol 2010 (Cicatrix...) : Moreover, TNF-alpha induced EMT was impaired by antagonists against bone morphogen proteins (BMP) 2/4, suggesting that BMP mediates the TNF-alpha induced EMT in human skin
Zhou et al., Zhongguo Zhong Yao Za Zhi 2010 : SA-B and BMP-7 can inhibit TGF-beta1 induced EMT in HK2
Bai et al., Development 2013 (Truncus Arteriosus, Persistent...) : To directly address the function of Vegfa repression in Bmp mediated EMT , we performed ex vivo explant cultures from Bmp4/7 and miR-17-92 mutant hearts