Xu et al., Nat Neurosci 2003
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These results show that MC4R signaling controls BDNF expression in the VMH and support the hypothesis that BDNF is an important effector through which MC4R signaling controls energy balance
Nicholson et al., J Neuroendocrinol 2007
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These findings demonstrate for the first time that activation of MC4R leads to an acute release of BDNF in the hypothalamus
Caruso et al., Mol Cell Endocrinol 2012
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Our results show for the first time that MC4R activation in astrocytes induces BDNF expression through cAMP-PKA-CREB pathway without involving NF-?B