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BCR — CD5
Text-mined interactions from Literome
Simarro et al., J Immunol 1999
:
A-SMase, PKC-zeta, and MAPK family members are key mediators of cell responses as diverse as proliferation, differentiation, and growth arrest and may contribute to
CD5 mediated modulation of TCR or
BCR signaling
Gary-Gouy et al., J Immunol 2007
(Leukemia, Lymphocytic, Chronic, B-Cell) :
Repeated
BCR stimulation of normal B cells
leads to anergy and
CD5 expression, both of which are features of CLL
Sindhava et al., Frontiers in immunology 2012
:
CD5 plays a major role in down regulation of
BCR responses in the B-1a cell subset
Dennehy et al., Eur J Immunol 1998
:
Both c-cbl and ras GAP have been proposed to suppress receptor mediated signaling, and may contribute to
CD5 mediated suppression of TCR or
BCR signaling