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BCL3 — CCND1
Text-mined interactions from Literome
Park et al., J Biol Chem 2006
(Carcinoma, Hepatocellular...) :
Up-regulation of
cyclin D1 by HBx is
mediated by
NF-kappaB2/BCL3 complex through kappaB site of cyclin D1 promoter ... Here we show that HBx up-regulates
cyclin D1 and that this process is
mediated by the NF-kappaB2 ( p52 )
/BCL-3 complex ... Moreover, impaired HBx mediated
BCL-3 up-regulation by small interfering RNA for BCL-3
reduced HBx mediated
cyclin D1 up-regulation ... From these results, we conclude that the up-regulation of
cyclin D1 by HBx is
mediated by the up-regulation of NF-kappaB2 ( p52 )
/BCL-3 in the nucleus
Wang et al., Toxicology 2010
(Translocation, Genetic) :
Moreover, we further demonstrated that
p52/Bcl3 complex formation
enhanced cyclin D1 expression through the cyclin D1 gene promoter via its kappaB site ... The up-regulation of
cyclin D1 mediated by the
p52-Bcl3 complex in response to low concentration arsenite might be important in assessing the health risk of low concentration arsenite and understanding the mechanisms of the harmful effects of arsenite