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STAT1 — VIP
Text-mined interactions from Literome
Delgado et al., J Immunol 2000
:
In agreement with the described Janus kinase (Jak)1/Jak2/STAT1/IRF-1 activation pathway,
VIP/PACAP inhibit Jak1/Jak2, STAT1 phosphorylation, and the binding of
STAT1 to the GAS sequence motif in the IRF-1 promoter
Bartoe et al., Brain Res Mol Brain Res 2002
:
While there are four STAT binding sites within gp130, only those surrounding Y905 and Y915 can mediate STAT1 activation ; these results indicate that
STAT1 may be
essential for normal gp130 stimulated
VIP and ChAT expression