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MUC13 — VIP
Text-mined interactions from Literome
Ho et al., Biochem Biophys Res Commun 2002
(Pancreatic Neoplasms) :
Secretion of MUC5AC
mucin from pancreatic cancer cells in
response to forskolin and
VIP
Kim et al., J Appl Physiol 2006
:
VIP ( 10 ( -7 ) M )
increased mucin secretion over 2 h. VIP ( 10 ( -9 ) to 10 ( -5 ) M ) stimulated mucin secretion in a dose dependent fashion ...
VIP induced
mucin secretion was partially blocked by a VIP receptor antagonist ( a chimeric VIP-pituitary adenylate cyclase activating peptide analog, VIP receptor antagonist ) at a 10-fold excess concentration ... We conclude that
VIP stimulated
mucin and lysozyme secretion was both time dependent and dose dependent and that NO neither stimulates nor inhibits mucus secretion in the ferret trachea
Amin et al., Am J Respir Cell Mol Biol 1991
:
To test whether simultaneous activation of the
VIP and muscarinic receptors or of beta-adrenoreceptors and muscarinic receptors
affect mucin secretion in a reciprocal manner, we studied some characteristics of the resultant physiologic response in human epithelial cells secreting radiolabeled mucin-like glycoprotein ( MLGP )
Turner et al., Arch Oral Biol 1990
:
The ED50 for
vasoactive intestinal peptide stimulated
mucin release was 0.12 +/- 0.05 nM, thus suggesting an activation anomaly in the vasoactive intestinal peptide receptor coupled signal transduction pathway at a point between cyclic AMP production and mucin release
Laburthe et al., Am J Physiol 1989
:
However,
VIP strongly
potentiated carbachol induced
mucin secretion, since carbachol alone and VIP plus carbachol induced a 1.6- and 3.6-fold increase of mucin secretion above basal, respectively
Hoosein et al., Regul Pept 1989
(Colonic Neoplasms) :
This is the first report of
VIP induced
mucin secretion in colon tumor cells
Hollande et al., In Vitro Cell Dev Biol Anim 1995
(Pancreatic Neoplasms) :
Effects of
VIP on the regulation of
mucin secretion in cultured human pancreatic cancer cells ( Capan-1 ) ... The
effects of
Vasoactive intestinal peptide (VIP) on
mucin secretion in the pancreatic cancer Capan-1 cell line were studied by Enzyme-linked-immunosorbent-assay ( ELISA ), and by light and electron microscopy using immunocytological methods
Culp et al., J Dent Res 1996
:
We isolated sublingual mucous acini from five-month-old and 24-month-old rats and compared the concentration responses for
mucin secretion
induced by
VIP and the muscarinic agonist, arecaidine propargyl ester (APE)
Plaisancié et al., Am J Physiol 1998
(Inflammation) :
VIP stimulated
mucin secretion was abolished by tetrodotoxin, whereas atropine was without effect