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IRF6 — SLC22A3

Text-mined interactions from Literome

Chantôme et al., J Biol Chem 2004 : Small interfering RNA mediated depletion of casein kinase II-alpha subunit also decreased NF-kappaB transcriptional activity and NOSII gene transcription in IL-1beta and LPS stimulated EMT-6J cells to the levels observed in EMT-6H cells treated in the same conditions
Zhao et al., J Surg Res 2011 : LPS can induce the expression of TGF-ß1 and a subsequent EMT in HIBEpiCs, and the inhibition of TGF-ß1 or Smad 2/3 could reverse this EMT, suggesting that LPS may play a potential role in the EMT of HIBEpiCs
Chen et al., Innate Immun 2012 (Disease Models, Animal...) : Here, a new role for LPS in promoting EMT is described ... LPS induced EMT was identified by examining the markers of EMT ... LPS induced EMT is critical for inflammation initiated metastasis ... Thus, resveratrol plays an important role in the inhibition of LPS induced EMT in mouse melanoma through the down-regulation of NF-?B activity
Jing et al., BMC medicine 2012 (Carcinoma, Hepatocellular) : Four HCC cell lines and a splenic vein metastasis of the nude mouse model were used to study the invasion ability of LPS induced HCC cells and the epithelia-mesenchymal transition (EMT) in vitro and in vivo ... The in vitro and in vivo experiments demonstrated that LPS could significantly enhance the invasive potential and induce EMT in HCC cells with TLR4 dependent ... Our results indicate that TLR4 signaling is required for LPS induced EMT , tumor cell invasion and metastasis, which provide molecular insights for LPS related pathogenesis and a basis for developing new strategies against metastasis in HCC
Cendan et al., J Surg Res 1996 (Mammary Neoplasms, Animal) : Incubation of EMT-6 with LPS and IFN stimulated arginine transport approximately 70 % over control levels at 12 hr and transport returned to basal levels at 24 hr. LPS/IFN stimulated EMT-6 cells produced 25 microM nitrite at 24 hr and reached a plateau of 55 microM nitrite at 48 hr