Gene interactions and pathways from curated databases and text-mining

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LTA — PTK2

Text-mined interactions from Literome

Wu et al., Life Sci 2006 : Here, we first showed that in rat cortical neuronal cells, LTA might activate protein tyrosine kinase ( PTK ) , phosphatidylcholine-specific phospholipase C ( PC-PLC ), and phosphatidylinositol-specific phospholipase C ( PI-PLC ) to induce protein kinase Cepsilon activation, which in turn induces extracellular signal regulated kinase ( ERK ) activation, finally inducing PGE ( 2 ) release and COX-2 synthesis
Worm et al., Eur J Immunol 1995 : Cross linking of the transmembrane phosphatase CD45 to CD40 by using goat-anti-mouse F ( ab ' ) 2 fragments strongly inhibits CD40 mediated LT alpha expression in human B cells, confirming the role of PTK activation in CD40 mediated induction of LT alpha expression