Hapke et al., J Biol Chem 2001
(Ovarian Neoplasms) :
Because integrin signaling alters gene expression patterns, we investigated whether the expression levels of uPA, uPAR , and PAI-1 are affected by ECM/integrin interactions
Sidenius et al., Cancer Metastasis Rev 2003
(Neoplasm Invasiveness...) :
Secondly, uPA/uPAR regulates cell/ECM interactions as an adhesion receptor for vitronectin (Vn) and through its capacity to modulate integrin function