Gene interactions and pathways from curated databases and text-mining

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HSP90AA1 — PI3

Text-mined interactions from Literome

Ortiz et al., American journal of physiology. Renal physiology 2004 : Flow also induced translocation of Hsp90 to the apical membrane ( from 35 +/- 2 to 57 +/- 2 % ; P < 0.05 ) in a PI3-kinase dependent manner
Wang et al., PloS one 2011 (Adenocarcinoma...) : Several compounds in the categories of HSP90 inhibitor, HDAC inhibitor, PPAR agonist, PI3K inhibitor , passed our screening to be the leading candidates
Khan et al., Mol Carcinog 2012 : It inhibited phosphatidylinositol-3-kinase (PI3K)/AKT activity, NF-?B, Hsp-90 , and survivin which may enhance the sensitivity of cells to apoptosis