Gene interactions and pathways from curated databases and text-mining

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EDN1 — PI3

Text-mined interactions from Literome

Su et al., Am J Physiol 1999 : Preincubation of smooth muscle cells with the tyrosine kinase inhibitor genistein ( 3 microM ) resulted in a significant inhibition of both C2 ceramide induced and endothelin induced PI 3-kinase activation and contraction
Raoch et al., Br J Pharmacol 2007 : The peptidase inhibitor CGS-26303 increases endothelin converting enzyme-1 expression in endothelial cells through accumulation of big endothelin-1
Wang et al., Am J Physiol 1998 : Both ceramide- and endothelin induced PI 3-kinase activation was inhibited by C3 exoenzyme pretreatment