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GRAP2 — PARP1
Text-mined interactions from Literome
Palsson et al., J Biol Chem 2000
:
Furthermore, constitutively active
Rap1AV12 inhibited
p38 MAPK activation by IL-1, consistent with Rap antagonizing Ras function
Zheng et al., Diabetes 2010
(Diabetes Mellitus, Experimental...) :
Simvastatin significantly upregulated PGC-1alpha ( P < 0.01 ), subsequently decreased Deltapsim ( P < 0.05 ) and ROS generation ( P < 0.01 ),
inhibited PARP activation ( P < 0.01 ), and further reduced VEGF expression ( P < 0.01 ) and
p38 MAPK activity ( P < 0.01 )