Gene interactions and pathways from curated databases and text-mining

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NPPA — PTK2

Text-mined interactions from Literome

Taskinen et al., Endocrinology 1999 : In conclusion, the findings that inhibitors of protein tyrosine kinase and protein phosphatase selectively modulated atrial wall stretch induced ANP secretion suggest a new mechanism involving endogenous protein tyrosine activity in the regulation of natriuretic peptide exocytosis from cardiac myocytes
Taskinen et al., Eur J Pharmacol 1994 : We examined the effects of a selective protein tyrosine kinase inhibitor, the isoflavonoid genistein, on haemodynamics and atrial natriuretic peptide (ANP) secretion in perfused rat heart preparations
Awazu et al., Kidney Int 1997 : These results demonstrate that ANP suppresses PDGFR PTK through GC-A probably by activating PKG