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KMT2A — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: KMT2A — TP53 (direct interaction, pull down) Dou et al., Cell 2005
• IRef Intact Interaction: Complex of KAT8-WDR5-MEN1-RBBP5-KMT2A-TP53 (association, pull down) Dou et al., Cell 2005

Text-mined interactions from Literome

Lee et al., Proc Natl Acad Sci U S A 2009 (Cell Transformation, Neoplastic...) : In support of redundant functions for MLL3 and MLL4 for some events, siRNA mediated down-regulation of both MLL3 and MLL4 is required to suppress doxorubicin-inducible expression of several p53-target genes
Li et al., Mol Cell 2009 : We further demonstrate that MOF-MSL1v1 is specifically required for optimal transcription activation of p53 target genes both in vitro and in vivo