◀ Back to KDR
KDR — PAF1
Text-mined interactions from Literome
Bernatchez et al., Br J Pharmacol 2001
:
2. Using specific inhibitors and Western blot analysis, we herein report that in bovine aortic endothelial cells ( BAEC ), VEGF
induces the synthesis of
PAF through the cascade activation of
Flk-1 receptor, phospholipase Cgamma ( PLCgamma ), protein kinase C ( PKC ) and p42/44 mitogen activated protein kinases ( MAPK )
Rechka et al., Can J Physiol Pharmacol 2010
:
We previously reported that VEGF mediated
PAF synthesis
involves the activation of the homodimeric tyrosine kinase receptor
VEGFR-2/R-2 , leading to the recruitment of p38 and p42/p44 mitogen activated protein kinases ( MAPKs ) and activation of secreted group V phospholipase A2 ( sPLA2-V )