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Sugimoto et al., Eur J Immunol 2003
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B42, but not A1, inhibited T cell proliferation along with down-regulation of IL-12 induced c-Myc expression and STAT5 phosphorylation
Masunaga et al., Transplantation 2005
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In contrast, although monomeric soluble CD40/Myc/His suppressed IL-12 production in a similar manner to that achieved by CD40Ig, it did not augment IL-2 production
Canda-Sánchez et al., Immunobiology 2009
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However, even though c-Myc is slightly up-regulated by IL-12 and partially mediates the proliferative effect of IL-12, this transcription factor was not found downstream of ERK1/2