Gene interactions and pathways from curated databases and text-mining

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FOS — HCRT

Text-mined interactions from Literome

Zheng et al., J Comp Neurol 2005 : Orexin-A projections to the caudal medulla and orexin induced c-Fos expression, food intake, and autonomic function
Vittoz et al., Eur J Neurosci 2008 (Synaptic Transmission) : HCRT significantly increased Fos-ir in VTA DA ( TH-ir ) neurons, primarily in a restricted population of small-to-medium sized DA neurons located within the caudomedial VTA
Riahi et al., Behav Pharmacol 2013 : Orexin did not enhance the rewarding efficacy of morphine ( 0.5 mg/kg ), but caused a reduction in hippocampal c-Fos