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BCL3 — CCND1

Text-mined interactions from Literome

Park et al., J Biol Chem 2006 (Carcinoma, Hepatocellular...) : Up-regulation of cyclin D1 by HBx is mediated by NF-kappaB2/BCL3 complex through kappaB site of cyclin D1 promoter ... Here we show that HBx up-regulates cyclin D1 and that this process is mediated by the NF-kappaB2 ( p52 ) /BCL-3 complex ... Moreover, impaired HBx mediated BCL-3 up-regulation by small interfering RNA for BCL-3 reduced HBx mediated cyclin D1 up-regulation ... From these results, we conclude that the up-regulation of cyclin D1 by HBx is mediated by the up-regulation of NF-kappaB2 ( p52 ) /BCL-3 in the nucleus
Wang et al., Toxicology 2010 (Translocation, Genetic) : Moreover, we further demonstrated that p52/Bcl3 complex formation enhanced cyclin D1 expression through the cyclin D1 gene promoter via its kappaB site ... The up-regulation of cyclin D1 mediated by the p52-Bcl3 complex in response to low concentration arsenite might be important in assessing the health risk of low concentration arsenite and understanding the mechanisms of the harmful effects of arsenite